Department Physics, Faculty of Science, Pacific University, Udaipur, Rajasthan, India
Department Chemistry, Faculty of Science, HNG University, Patan, Gujarat, India
In the present generation, there is a commercial demand for silver nanoparticles due to their widespread applications. In this study, silver nanoparticles were synthesized using Carica papaya peel extract as a reducing agent. The synthesized nanoparticles were characterized under UV-Visible spectrophotometer, FTIR, SEM, XRD and TEM. UV-Visible spectrophotometer was used to monitor the formation of silver nanoparticles. The TEM analysis shows that the silver nanoparticles have an average size of 50 nm. X-ray diffraction analysis showed that the particles were crystalline in nature. The antibacterial activity of silver nanoparticles was performed on various gram-positive and gram-negative bacteria. These silver nanoparticles showed a significant cytotoxic effect against both, MCF-7 and Hep-2 cells.
Laura, Ch., Singaravelu, V., Manjusr,i M., Amar Kumar M., “Biosynthesis of silver nanoparticles using murrayakoenigii (curry leaf): An investigation on the effect of broth concentration in reduction mechanism and particle size”, Adv. Mat. Lett, 6 (2011) 429-434.
Karimzadeh R., Mansour N., “Effect of concentration on the thermo-optical properties of colloidal silver nanoparticles”, J. Pptlastec, 5 (2010) 783-789.
Sun, R. W., Chen, R., Chung, N. P., Ho, C M., Lin, C. L., Che, C. M., “Silver nanoparticles fabricated in Hepes buffer exhibit cytoprotective activities toward HIV-1 infected cells”, Chem commun (camb), 28 (2005) 5059-5061.
Ramesh Kumar, P., Singaravelu, V., Manjusri M., Amar Kumar M., Nallani S., “Soybean (Glycine max) leaf extract based green synthesis of palladium nanoparticles”, JBNB, 3 (2012) 14-19.
Cheong, S., Watt, J. D., Tilley, R. D., “Shape control of platinum and palladium nanoparticles for catalysis”, Nanoscale, 10 (2010) 2045-2053.
Jha, A. K., Prasad, K., Kulkarni, A. R., “Yeast mediated synthesis of silver nanoparticles”, International Journal of Nanoscience and Nanotechnology, 4 (2008) 17-22.
Chen, H., Wei, G., Ispas, A., Hickey, S. G., Iler, A. E., “Synthesis of palladium nanoparticles and their applications for surface-enhanced raman scattering and electrocatalysis”, The Journal of Physical Chemistry C, 50 (2010) 21976-21981.
Vala, A. K., Shah, S., “Rapid synthesis of silver nanoparticles by a marine-derived fungus Aspergillus Niger and their antimicrobial potentials”, International journal of nanoscience and nanotechnology, 8 (2012) 197-206.
Gopidas, K. R., Whitesell, J. K,. Fox, M. A., “Synthesis, characterization, and catalytic applications of a Palladium-nanoparticle-cored dendrimer”, Nano Letters, 12 (2003) 1757-1760.
Honary, S., Gharaei-Fathabad, E., Khorshidi Paji, Z., Eslamifar, M., “A novel biological synthesis of gold nanoparticle by enterobacteriaceae family”, Tropical Journal of Pharmaceutical Research, 11 (2012) 887-891.
Gholami Shabani, M., Gholami Shabani, Z., Shams Ghahfarokhi, M., Akbarzadeh, A., Riazi, Gh., Razzaghi Abyaneh, M., “Biogenic approach using Sheep milk for the synthesis of Platinum nanoparticles: The role of milk protein in Platinum reduction and stabilization”, International journal of nanoscience and nanotechnology, 12 (2016) 199-206.
Sali Syed, M., Habib Ali Bokhari S., “Gold nanoparticle-based microbial detection and identification”, J. Biomed. Nanotech, 7 (2011) 229-237.
Nam J., Won N., Jin H., Chung H., Kim S., “PH-induced aggregation of gold nanoparticles for photothermal cancer therapy”, J. Am. Chem. Soc, 131 (2009) 13639–13645.
Rai, M., Yadav, A., Cade, A., “Current Trends in Phytosynthesis of Metal Nanoparticles”, Critical Reviews in Biotechnology, 28 (2008) 277-284.
Kumar, V., Yadav, S. C., Yadav, S. K., “Syzygiumc- mini leaf and seed extract mediated biosynthesis of silver nanoparticles and their characterization”, Journal of Chemical Technology & Biotechnology, 85 (2010) 1301-1309
Zhan, G., Huang, J., Du, M., Abdul-Rauf, I., Ma, Y., Li, Q., “Green synthesis of Au-Pd bimetallic nanoparticles: single-step bioreduction method with plant extract”, Materials Letters, 65 (2011) 2989- 2991.
Nadagouda, M. N., Varma, R. S., “Green synthesis of silver and palladium nanoparticles at room temperature using coffee and tea extract, Green Chemistry”, 10 (2008) 859-862.
Philip, D., “Green synthesis of gold and silver nanoparticles using hibiscus rosa sinensis”, Physica E. 42 (2010) 1417-1424.
Das, R. K., Borthakur, B. B., Bora, U., “Green synthesis of gold nanoparticles using ethanolic leaf extract of centella asiatica”, Materials Letters, 64 (2010) 1445-1447.
Kaviya, S., Santhanalakshmi, J., Viswanathan, B., Muthumary, J., Srinivasan, K., “Biosynthesis of silver nanoparticles using citrus sinensis peel extract and its antibacterial activity,” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 79 (2011) 594-598.
Song, J. Y., Kim, B. S., “Biological synthesis of bimetallic Au/Ag nanoparticles using persimmon (Diopyros kaki) leaf extract”, Korean Journal of Chemical Engi- neering, 25 (2008) 808-811.
Song, J. Y., Kwon, E. Y., Kim, B. S., “Biological synthesis of platinum nanoparticles using diopyros kaki leaf extract”, Bioprocess and Biosystems Engineering, 33 (2010) 159-164.
Shakeel, A., Saifullah, M. A., Babu Lal, S., Saiqa, I., “Green synthesis of silver nanoparticles using Azadirachtaindica aqueous leaf extract”, Journal of Radiation Research and Applied Sciences, 9 (2016) 1-7.
Varaprasad, T., Govindh, B., Venkateswara, B., “Green Synthesized Cobalt Nanoparticles using Asparagus racemosus root Extract & Evaluation of Antibacterial activity”, Int. J. Chem. Tech. Research, 10 (2017) 339-345.
Hoti, M. S. L., Mehlhorn, H., Barnard, D. R., Benelli, G., “Novel synthesis of silver nanoparticles using Bauhinia variegata: a recent ecofriendly approach for mosquito control”, Parasitol Res., 115 (2016) 723-733.
Vibhute, S. K., Kasture, V. S., Kendre, P. N., Wagh, G. S., “Synthesis of silver nanoparticles from Moringa Oleifera : formulation and evaluation agSainstcadidia albicans”, Indo American Journal of Pharmaceutical Research, 4 (2014) 1581-1587.
Rout, Y., Behera, S., Ojha, A. K., Nayak, P. L., “Green synthesis of silver nanoparticles using Ocimum sanctum (Tulashi) and study of their antibacterial and antifungal activities”, Journal of Microbiology and Antimicrobials, 4 (2012) 103-109.
Sundararajan, B., Ranjitha Kumari, B. D., “Biosynthesis of silver nanoparticles in Lagerstroemia Speciosapers and their antimicrobial activities”, International journal of pharmacy and pharmaceutical sciences, 6 (2014) 30-34.
Sondi, I., Salopek-sondi, B., “Silver nanoparticles as antimicrobial agent: a case study on E. Colias a model for gram negative bacteria”, J-colloid interface sci, 275 (2004) 177-182.
Palaniyandi, V., Jayabrata, D., Raman, P., Baskaralingam, V., Kannaiyan, P., “Greener approach for synthesis of antibacterial silver nanoparticles using aqueous solution of neem gum (AzadirachtaindicaL.)”, Industrial crops and products, 66 (2015) 103-109.
John, T., Parmar, K. A., Kotval, S. C., & Jadhav, J. (2021). Synthesis, Characterization, Antibacterial and Anticancer Properties of Silver Nanoparticles Synthesized from Carica Papaya Peel Extract. International Journal of Nanoscience and Nanotechnology, 17(1), 23-32.
T. John; K. A. Parmar; Sh. C. Kotval; J. Jadhav. "Synthesis, Characterization, Antibacterial and Anticancer Properties of Silver Nanoparticles Synthesized from Carica Papaya Peel Extract". International Journal of Nanoscience and Nanotechnology, 17, 1, 2021, 23-32.
John, T., Parmar, K. A., Kotval, S. C., Jadhav, J. (2021). 'Synthesis, Characterization, Antibacterial and Anticancer Properties of Silver Nanoparticles Synthesized from Carica Papaya Peel Extract', International Journal of Nanoscience and Nanotechnology, 17(1), pp. 23-32.
John, T., Parmar, K. A., Kotval, S. C., Jadhav, J. Synthesis, Characterization, Antibacterial and Anticancer Properties of Silver Nanoparticles Synthesized from Carica Papaya Peel Extract. International Journal of Nanoscience and Nanotechnology, 2021; 17(1): 23-32.