1
Biomaterial Engineering group, Isfahan University of medical sciences, Isfahan, Iran
2
Department of Nanotechnology Engineering, Faculty of Advanced Sciences and Technologies, University of Isfahan, Isfahan 81746-73441, Iran
Abstract
Biodegradable elastomeric materials are gaining extensive attention in the field of soft tissue engineering. Poly (glycerol sebacate) (PGS) is a novel biocompatible elastomer in this scope. However this polymer has poor mechanical properties especially when the molar ratio of glycerol is higher than sebacic acid. Calcium Titanate (CaTiO3) is a biocompatible ceramic with some degrees of piezoelectricity, which is in favor of cell growth. In this study; Calcium Titanate is synthesized at nano-scale by sol-gel method and dispersed into as-synthesized PGS pre-polymer in weight-ratio of 5:95 for CaTiO3 and PGS, respectively. This waxy material was cured to achieve the final product. The molar ratio of glycerol and sebacic acid for the synthesis of PGS was 1:0.8, respectively. X-ray diffraction (XRD) test confirms successful synthesis of CaTiO3 and the nano-scale of crystals are approved by transmission electron microscopy (TEM) Image. Fourier transform infrared (FTIR) spectroscopy has revealed a chemical bond between the two phases after addition of ceramic into pre-polymer. Distribution of CaTiO3 nano-structures in the polymeric matrix is shown by Scanning Electron Microscopy (SEM).
Naser,R. , Zargar Khrazi,A. and Dini,G. (2016). Fabrication of PGS/CaTiO3 Nano-Composite for Biomedical Application. International Journal of Nanoscience and Nanotechnology, 12(2), 103-108.
MLA
Naser,R. , , Zargar Khrazi,A. , and Dini,G. . "Fabrication of PGS/CaTiO3 Nano-Composite for Biomedical Application", International Journal of Nanoscience and Nanotechnology, 12, 2, 2016, 103-108.
HARVARD
Naser R., Zargar Khrazi A., Dini G. (2016). 'Fabrication of PGS/CaTiO3 Nano-Composite for Biomedical Application', International Journal of Nanoscience and Nanotechnology, 12(2), pp. 103-108.
CHICAGO
R. Naser, A. Zargar Khrazi and G. Dini, "Fabrication of PGS/CaTiO3 Nano-Composite for Biomedical Application," International Journal of Nanoscience and Nanotechnology, 12 2 (2016): 103-108,
VANCOUVER
Naser R., Zargar Khrazi A., Dini G. Fabrication of PGS/CaTiO3 Nano-Composite for Biomedical Application. International Journal of Nanoscience and Nanotechnology, 2016; 12(2): 103-108.
