Iranian Nanotechnology SocietyInternational Journal of Nanoscience and Nanotechnology1735-700421220250630Nano Chitosan-Paracetamol Composite as a Potential Lung Cancer Inhibitor: Synthesis, Characterization, and Cytotoxicity Studies.596673795910.22034/ijnn.2026.2053411.2633ENBahaa K.Al-GhanimiDepartment of Anaesthesia and Critical Care, Al-Taff University College, Kerbala 56001, Iraq.0000-0003-1369-063XOusama W.AbdulnabiUniversity of Kerbala/ College of education for pure sciences/ Department of chemistry0009-0000-5228-9932Hussein H.Al-GhanimiBiomedical Engineering Department, College of Engineering, University of Warith Al-Anbiyaa, Karbala 56001, Iraq.0000-0003-2973-393XMohammad N.AL-BaiatiDepartment of Chemistry, College of Education for Pure Sciences, University of Kerbala, Karbala, 56001, Iraq.0000-0001-6947-2629Khawla I.Abd NusaifCollege of Veterinary Medicine, University of Kerbala, Karbala, 56001. IraqJournal Article20250213Nanoparticles have been used in many areas of life, including medicine, due to the properties they possess that distinguish them from conventional particles. In the current study, Nano chitosan-paracetamol was synthesized, and the synthesized nanoparticles were characterized using FT-IR and 1H-NMR techniques. A drug was created using a variety of properties, and its anticancer properties against lung cancer A549 cell lines were investigated in vitro. It was determined what kinds of linkages existed between amino acids and nano-chitosan medications. The outcomes demonstrated how well the medications work to stop cancer cells from spreading. The effect of nano-chitosan on the toxicity of lung cancer cells (A549) was shown only with an IC50 = 137.87 µg/ml. However, when paracetamol was loaded onto nano-chitosan, better results were achieved, with a toxicity of lung cancer cells (A549) with an IC50 = 109.49 µg/ml. The result of gene expression of p53 gene for the control group was (1.00 + 0.0 N=3) and when exposed to nano chitosan only, a significant mutation appeared and the result was (2.933 + 0.2028 N=3) but when exposed to the prepared nano drug, the result became (4.100 + 0.1528 N=3). The rationale is the pressing requirement that the medication maintain its benefits for an extended duration until it more effectively reaches particular body parts without endangering other body parts. When the synthesis of Nano-Chitosan-Paracetamol was tested for biological activity, it was found to be highly successful in preventing the lung cancer cells from spreading quickly.https://www.ijnnonline.net/article_737959_3366c88e99b8b4cfbcb27cf0d4f44fc7.pdfIranian Nanotechnology SocietyInternational Journal of Nanoscience and Nanotechnology1735-700421220250630Enhancing the Ionic Conductivity of Corn Starch-based Solid Polymer Electrolytes Utilizing Inorganic Filler677573796710.22034/ijnn.2026.2043238.2581ENReffy AldoAmantaDepartment of Engineering Physics, Faculty of Industrial Technology and Systems Engineering, Institut Teknologi Sepuluh Nopember, Surabaya, IndonesiaSylvia AyuPradanawatiMechanical Engineering, Universitas Pertamina, Jakarta, Indonesia0000-0002-5520-6669Yatim LailunNi'mahDepartment of Chemistry, Faculty of Science and Data Analytics, Institut Teknologi Sepuluh Nopember, Surabaya, IndonesiaAzzah DyahPramataMaterial and Metallurgical Engineering, Faculty of Industrial Technology and Systems Engineering, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia0000-0002-4868-3547LukmanNoerochimMaterial and Metallurgical Engineering, Faculty of Industrial Technology and Systems Engineering, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia0000-0002-3013-4259Nur LailaHamidahDepartment of Engineering Physics, Faculty of Industrial Technology and Systems Engineering, Institut Teknologi Sepuluh Nopember, Surabaya, Indonesia0000-0003-0777-4095Journal Article20241012For safety reasons, solid polymer electrolyte (SPE) has been developed as an alternative to liquid electrolyte. Nevertheless, the research advancement of all-solid-state energy storage is impeded by the io transport between solid-solid interfaces. The integration of fillers into the polymer matrices is illustrated as a prevalent approach to improve ion transport. The objective of this study is to enhance the ionic conductivity of corn starch-based SPE by incorporating zinc oxide (ZnO), vanadium oxide (V2O5), and cerium oxide (CeO2) as inorganic fillers through the solution casting method. X-ray diffraction (XRD) indicated that the incorporation of 20 wt.% ZNO resulted in the highest amorphous state of 93%, hence enhancing the ionic conductivity due to increased pathways for ion transfer. This finding was further supported by the analysis of the glass-transition temperature (Tg), recorded at 25.6°C via digital scanning calorimetry (DSC), hence reinforcing the data related to the amorphous state. The shift of the CH2OH group from 1330 to 1321 cm-1 in Fourier transform infrared spectroscopy (FTIR) indicates the presence of filler in the polymer structure. Moreover, the increased amorphous structure leads to the formation of pores, as evidenced by scanning electron microscopy (SEM), which enhances the ionic conductivity of the solid polymer electrolyte (SPE). The ionic conductivity of SPE containing 20 wt% ZNO at ambient temperature is 3.021 x 10-3 S/cm, as measured by electrochemical impedance spectroscopy (EIS). This result is comparable to the ionic conductivity of liquid electrolyte (10-4 – 10-2 S/cm), indicating possible applicability as a solid electrolyte.https://www.ijnnonline.net/article_737967_1acf8a4371b92c211a3fd4c026f445e1.pdfIranian Nanotechnology SocietyInternational Journal of Nanoscience and Nanotechnology1735-700421220250630Investigating the Morphological and Functional Group Characteristics of Sol-Gel Synthesized Silica Nanoparticles Derived from Natural and Commercial Precursors778773796810.22034/ijnn.2026.2053759.2634ENSyukurDaulayDepartment of Metallurgical and Materials Engineering-Faculty of Engineering Universitas Indonesia, Depok, West Java, Indonesia.0000-0002-8399-8907Akhmad HermanYuwonoDepartment of Metallurgical and Materials Engineering-Faculty of Engineering Universitas Indonesia, Depok, West Java, Indonesia.0000-0001-9887-6446GusaimasAkbarDepartment of Metallurgical and Materials Engineering-Faculty of Engineering Universitas Indonesia, Depok, West Java, Indonesia.0009-0003-5445-4091DonantaDhaneswaraDepartment of Metallurgical and Materials Engineering-Faculty of Engineering Universitas Indonesia, Depok, West Java, Indonesia.0000-0001-6667-8058NofrijonSofyanDepartment of Metallurgical and Materials Engineering-Faculty of Engineering Universitas Indonesia, Depok, West Java, Indonesia.0000-0001-7814-9022Bambang HeruSusantoDepartment of Chemical Engineering-Faculty of Engineering Universitas Indonesia, Depok, West Java, Indonesia.0000-0002-3338-2792AgusIsmailProgram Studi Teknik Industri Universitas Mercu Buana, Jakarta, IndonesiaJournal Article20250219Silica nanoparticles (SNPs) are widely investigated in science and largely used in various strategic applications. Due to the abundant source of silica in the beach, there is a necessity to obtain naturally derived SNPs comparable with those synthesized from commercial precursors. Therefore, this research aimed to effectiveness of sol-gel method to produce sodium silicate (Na2SiO3) by mixing silica sand with sodium hydroxide and neutralizing using the concentrated hydrochloric solution. SNPs were characterized with X-ray diffraction (XRD), Fourier Transform Infrared (FTIR) spectroscopy, and Scanning Electron Microscopy (SEM). For comparison purposes, the sol-gel process was also carried out with commercial sodium silicate and tetraethyl orthosilicate (TEOS) precursors to obtain synthetic SNPs, while the fabricated SNPs were used as the standard. The result showed that the synthetic and fabricated had a typical peak for silica at a wave number of 950 cm-1. Phase characterization showed the characteristics of silica nanoparticles at a 2θ angle of 22°, and silica crystal peaks were still visible in the synthesis of SNPC600 and SNPN600. Crystallite size calculation obtained 19.84, 4.40, 4.31, and 2.94 nm for SNPN600, SNPC600, SNPTEHN600, and XFNANO, respectively. Microstructural analysis showed a uniform distribution of particles in SNPN600 and SNPTEHN600, along with an inhomogeneous distribution in SNPC600.https://www.ijnnonline.net/article_737968_558f1e52d5c9418e68877c1eeaf3ea1f.pdfIranian Nanotechnology SocietyInternational Journal of Nanoscience and Nanotechnology1735-700421220250630Laser-Assisted Synthesis and Modification of Nanodiamond/Gold Nanocomposites: A Novel Therapeutic Approach for Burn Wound Healing in Diabetic Rats899673797010.22034/ijnn.2026.2050371.2624ENFaribaMehradniaDepartment of Atomic and Molecular Physics, Faculty of Physics, Alzahra University, Tehran, IranBATOOLSAJADDepartment of Atomic and Molecular Physics, Faculty of Physics, Alzahra University, Tehran, IranFaridehBahramiDepartment of Physiology and Medical Physics, Faculty of Medicine, Baqyatoolah University of Medical Sciences, Tehran, IranSeyedeh SorayaMousavitehranSeyyed AhadBagheriDepartment of Physiology and Medical Physics, Faculty of Medicine, Baqyatoolah University of Medical Sciences, Tehran, IranSeyyed HomayounSadraeiDepartment of Anatomy, Faculty of Medicine, Baqyatoolah University of Medical Sciences, Tehran, IranJavadRaouf SarshooriDepartment of Anatomy٫Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran,Iran.Journal Article20250110This study presents a novel laser-assisted method for synthesizing a nanocomposite of nanodiamonds (NDs) and gold nanoparticles (Au NPs). Our approach uniquely uses laser treatment to simultaneously create the nanocomposite and modify the ND structure, enhancing its biomedical properties.<br>We evaluated the therapeutic potential of this nanocomposite in diabetic wound healing studies using highly diabetic rat models, where it demonstrated superior efficacy compared to other treatments. Individual treatments with NDs and Au NPs significantly improved over the control group. higher wound closure rates by Day 7 compared to ND, AuNP, and control groups (p < 0.001). Re-epithelialization analysis on Day 21 confirmed superior regeneration in the ND/AuNP group versus all other groups (p < 0.001).<br>These results highlight the promise of our innovative synthesis strategy for advancing therapeutic applications in diabetic wound healing.https://www.ijnnonline.net/article_737970_3a30c8b30adfa6b672fec3a1d462b6d3.pdfIranian Nanotechnology SocietyInternational Journal of Nanoscience and Nanotechnology1735-700421220250630Uncovering the Properties of Nanoemulsions Loaded with Boswellia Serrata Essential Oil: A Synthesis, Characterization, Stability and in Vitro Biological Activity9710773797110.22034/ijnn.2026.2052707.2630ENArun DevSharmaDept of biotechnology. Lyallpur khalsa college jalandhar punjabRavindreshChhabraDepartment of Biochemistry, Central University of Punjab, VPO Ghudda-151401 Bathinda. IndiaPuneetJainDepartment of Biochemistry, Central University of Punjab, VPO Ghudda-151401 Bathinda. IndiaInderjeetKaurDepartment of Biotechnology, Lyallpur Khalsa College, Mohyal Nagar Jalandhar, Punjab (144008), IndiaAmritaChauhanDepartment of Biotechnology, Lyallpur Khalsa College, Mohyal Nagar Jalandhar, Punjab (144008), IndiaJournal Article20250205Guggul essential oil (GEO) derived from Boswellia serrata is utilized in Ayurveda as traditional and complementary medicine. However, because of their chemical instability, volatile in nature, strong aromas, and poor absorption, the use of GEO is restricted. The objectives of this work were to create Guggul essential oil-based O/W (oil/water) nanoemulsions (GNE) and evaluate their biological potential. GNE were prepared by using Tween-80, Ethanol and SDS using ultrasonicator. Through the use of Particle Size Analyzer, UV, fluorescence, and FT-IR methods, physiological characterization was completed. Numerous biological activities, such as anti-inflammatory, anti-diabetic, anti-bacterial and anti-cancer potential was estimated. The spherical-shaped nanoemulsions had globule sizes of 220 nm, a zeta potential of -35.30mV, a polydispersity index of 0.25, and a drug entrapment efficiency of 96.5% (w/v). GNE's in vitro drug release occurred slowly roughly 45% at six hours. GNE exhibited remarkable antioxidant potential such as: 46% for scavenging DPPH radicals, 33% for scavenging ABTS radicals, 20% for scavenging hydroxyl radicals, and 81% for the iron chelating test. Antibacterial activity was observed with inhibition zone ranged from 0.3 to 1.1 cm against G+ and G- bacteria. After being exposed to 5 µl of GNE, 20% of HeLa cells were viable. GNE exhibited 70% inhibition of α-amylase activity at its higher dose of 250 µL. GNE remained stable even for 50 days. Kinetics of drugs showed that nanoemulsions displayed the Higushi model. GNE potential in the pharmaceutical, food industry has also been explored.https://www.ijnnonline.net/article_737971_6a03ba6ac33b90a23cf2185783b263a1.pdfIranian Nanotechnology SocietyInternational Journal of Nanoscience and Nanotechnology1735-700421220250601Nanotechnology in Wastewater Treatment: Innovations for a Sustainable Future - A Review10912173797210.22034/ijnn.2026.2054339.2637ENDalilaZianiDepartment of Geotechnics and Hydraulics, Faculty of Civil Engineering, University of Science and Technology Houari Boumediene, Bab-Ezzouar, Algiers, Algeria0000-0003-0488-8679AzizMaaliouDepartment of Geotechnics and Hydraulics, Faculty of Civil Engineering, University of Science and Technology Houari Boumediene, Bab-Ezzouar, Algiers, Algeria0000-0002-8332-0573LeilaDjekouneUniversity of Science and Technology Houari Boumediene, Faculty of Mechanical and Process Engineering, Department of Environmental Engineering, Laboratory of Industrial Process Engineering Sciences (LSGPI); BP 32, El-Alia-Bab-Ezzouar,0000-0001-9044-1667AbderzakMoussouniUniversity Center Abdelhafid Boussouf Mila, Institute of Science and Technology, Department of Civil Engineering and Hydraulics, Laboratory of Geotechnical and Hydrological Environment (LEGHYD); BP 26 RP, Mila, 43000, Algeria0009-0000-5147-2938Journal Article20250304This study is a summary of recent nanotechnology developments for wastewater treatment and how effective nanomaterials are in purifying and decontaminating water. A literature review has identified the most promising nanomaterials: carbon nanotubes, metal nanoparticles and nanostructured membranes, which can adsorb and break down organic and inorganic pollutants. The studies mainly focused on characterizing the physical and chemical properties of these nanomaterials and testing their efficiency in treating wastewater in different environments. The results show that nanotechnologies are not only more efficient than traditional methods but also use less energy and produce less toxic by-products. In summary, nanotechnologies offer exciting opportunities for better and more sustainable wastewater treatment, but more research is needed to evaluate long-term environmental impact and safety before implementation.https://www.ijnnonline.net/article_737972_33cf2592a8792bbd598029a591a76820.pdf