Iranian Nanotechnology Society International Journal of Nanoscience and Nanotechnology 1735-7004 20 3 2024 09 01 Coal Tar Pitch / Graphene / Polyglycine Modified Pencil Graphite Electrode for Simultaneous Electrochemical Detection of Guanine and Adenine 171 183 721798 10.22034/ijnn.2025.2014213.2446 EN Şeyma Korkmaz Chemistry Department, Institute of Science, Necmettin Erbakan University, Konya, Turkey Nesim İslamoğlu Chemistry Department, Institute of Science, Necmettin Erbakan University, Konya, Turkey 0000-0001-9244-7608 Ecir Yılmaz Chemistry Department, Ahmet Keleşoğlu education Faculty, Necmettin Erbakan University, Konya, Turkey Zafer Üstündağ Chemistry Department, Science and Art Faculty, Dumlupınar University, Kütahya, Turkey İbrahim Ender Mülazımoğlu Chemistry Department, Ahmet Keleşoğlu education Faculty, Necmettin Erbakan University, Konya, Turkey 0000-0003-1676-2870 Ayşen Demir Mülazımoğlu Chemistry Department, Ahmet Keleşoğlu education Faculty, Necmettin Erbakan University, Konya, Turkey Journal Article 2023 10 24 <em>   In this study, a coal tar pitch / graphene / polyglycine modified pencil graphite electrode sensor was developed for the quantitative detection of guanine and adenine, two of the most important components of DNA and RNA. Therefore, the determination of guanine and adenine is of great significance. The coal tar pitch / graphene / polyglycine modified pencil graphite electrode was characterized by scanning electron microscope. Cyclic voltammetry, electrochemical impedance spectroscopy, linear sweep voltammetry, and square wave voltammetry techniques were employed to analyze the behavior of guanine and adenine on coal tar pitch/ graphene/ polyglycine modified pencil graphite electrode in 0.1 M of H₂SO₄. Under the optimal conditions, electrical signals were linear over the concentration ranges from 1.0 to 25 μM and 10.0 to 140 μM for simultaneous determination of guanine and adenine with the detection limit as low as 0.6 μM and 6 μM, respectively. As a candidate for developing electrochemical sensors, the coal tar pitch/ graphene/ polyglycine modified pencil graphite electrode sensor presented here has a wide range of potential applications.</em> https://www.ijnnonline.net/article_721798_6ce15f92483d42b604115ad788800a7f.pdf