Iranian Nanotechnology Society International Journal of Nanoscience and Nanotechnology 1735-7004 14 3 2018 08 01 Selective Potentiometric Sensor for Isoniazid Ultra-Trace Determination Based on Fe3O4 Nanoparticles Modified Carbon Paste Electrode (Fe3O4/CPE) 241 249 32222 EN R. Shabani Department of Chemistry, Firoozabad Branch, Islamic Azad University, Firoozabad, Iran. Z. Lakhaiy Rizi Department of Chemistry, Firoozabad Branch, Islamic Azad University, Firoozabad, Iran. R. Moosavi Young Researchers and Elite Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran. Journal Article 2016 10 23 <em>   Significant effects of magnetic iron oxide (Fe₃O₄) nanoparticles on the potentiometric behavior of carbon paste electrode for bio determination of Isoniazid aromatic drug (INH) were studied. The electrochemical performance of modified Fe₃O₄/CPE was investigated. The constructed Fe₃O₄/CPE showed high precision, sensitivity and selectivity, for successfully determination of ultra-trace concentration of INH samples. In this research, pH effects, optimal condition for electrode and interfering Ions, on electrode response were investigated. The best potential response for Fe₃O₄/CPE was obtained with electrode composition of 0.012 g magnetic NPs, 0.006 g silicon oil and 0.060 g graphite powder at pH 6.5 and showed such a low detection limit as 3.09×10⁻¹³ mol L⁻¹ INH.</em> https://www.ijnnonline.net/article_32222_28c4661da88dffe967089b43666e4844.pdf