Bhunia, T. (2018). Different PVA-Hydroxypropyl Guar Gum Irradiated Nanosilica Composite Membranes for Model Drug Delivery Device. International Journal of Nanoscience and Nanotechnology, 14(3), 187-195.
T. Bhunia. "Different PVA-Hydroxypropyl Guar Gum Irradiated Nanosilica Composite Membranes for Model Drug Delivery Device". International Journal of Nanoscience and Nanotechnology, 14, 3, 2018, 187-195.
Bhunia, T. (2018). 'Different PVA-Hydroxypropyl Guar Gum Irradiated Nanosilica Composite Membranes for Model Drug Delivery Device', International Journal of Nanoscience and Nanotechnology, 14(3), pp. 187-195.
Bhunia, T. Different PVA-Hydroxypropyl Guar Gum Irradiated Nanosilica Composite Membranes for Model Drug Delivery Device. International Journal of Nanoscience and Nanotechnology, 2018; 14(3): 187-195.
Different PVA-Hydroxypropyl Guar Gum Irradiated Nanosilica Composite Membranes for Model Drug Delivery Device
Department of Chemistry, Bijoy Krishna Girls’ College, Howrah, West Bengal, India-711101.
Abstract
High strength and elastic biodegradable membranes are of great demand in modern technology. Similar membranes have been developed by irradiating different weight poly (vinyl alcohol) (PVA) – hydroxypropyl guar gum (HPG) blends and followed by combining with ex situ nanosilica. Polarized light microscopic (PLM) study indicates that electron beam irradiation produced crosslinks and developed crystallinity in PVA-HPG matrix. Atomic force microscopic analysis shows that 1 wt.% nanosilica produced finer dispersion in both high and low molecular weight PVA-HPG matrix resulting nearly 4.5 times higher mechanical strength and controlled swelling-deswelling property e.g., low molecular weight PVA with 1wt% nanosilica content show swelling ratio 3.5. Greater nanosilica and PVA-HPG interaction was observed in low molecular PVA-HPG composite membranes than high molecular weight PVA-HPG composite membranes which finally showed better efficacy towards drug retention and elution under physiological condition.
Top