TY - JOUR ID - 244186 TI - Ionic Liquid Attached to Colloidal Silica ‎Nanoparticles as Catalyst for the ‎Synthesis of Pyrimidines JO - International Journal of Nanoscience and Nanotechnology JA - IJNN LA - en SN - 1735-7004 AU - Shahbazi-Alavi, H. AU - safaei-Ghomi, J. AD - ‎Young Researchers and Elite Club, Kashan Branch, Islamic Azad University, P.O. Box ‎‎87159-98151, Kashan, Iran AD - Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Iran Y1 - 2021 PY - 2021 VL - 17 IS - 2 SP - 133 EP - 140 KW - Pyrimidine KW - Heterogeneous catalyst KW - Ionic liquid KW - Colloidal silica nanoparticles KW - Microwave KW - ‎Ultrasound irradiation.‎ DO - N2 -    Bis (1(3-trimethoxysilylpropyl)-3-methyl-imidazolium) copper tetrachloride tethered to colloidal silica nanoparticles have been used as an efficient catalyst for the preparation of 2,4-diamino-6-arylpyrimidine-5-carbonitrile derivatives by the one-pot reaction of aromatic aldehydes, malononitrile, and guanidinehydrochlorideunder conventional heating, microwave and ultrasound irradiations. The catalyst was characterized by 1H NMR spectroscopy,dynamic light scattering (DLS), scanning electron microscope (SEM), energy dispersive spectroscopy (EDS) and thermogravimetric analysis (TGA). The remarkable advantages of this methodology are easy work-up, short reaction times, high to excellent product yields, operational simplicity, low catalyst loading and use of ultrasonic irradiation as a valuable and powerful technology. UR - https://www.ijnnonline.net/article_244186.html L1 - https://www.ijnnonline.net/article_244186_7634516fc744542370455d098d895176.pdf ER -