Electrochemical Behavior and Determination ‎of Phenylephrine at the Multi-Walled Carbon ‎Nanotubes/ionic Liquid Nanocomposite ‎Modified Electrode in the Presence of ‎Acetaminophen

Habibi, B.; Ayazi, Z.; Zalvand, Firooz

Electrochemical Behavior and Determination ‎of Phenylephrine at the Multi-Walled Carbon ‎Nanotubes/ionic Liquid Nanocomposite ‎Modified Electrode in the Presence of ‎Acetaminophen

Document Type : Research Paper

Authors

B. Habibi ¹

Z. Ayazi ¹

Firooz Zalvand ²

¹ Electroanalytical Chemistry Laboratory, Department of Chemistry, Faculty of Sciences, ‎Azarbaijan Shahid Madani University, Tabriz 53714-161, Iran.‎

² Electroanalytical Chemistry Laboratory, Department of Chemistry, Faculty of Sciences, Azarbaijan Shahid Madani University, Tabriz 53714-161, Iran.

Abstract

A simple and high sensitive electrochemical method was developed for determination of phenylephrine (PHE) in the presence of acetaminophen (AC) at the carbon-ceramic electrode modified by multi-walled carbon nanotubes/ionic liquid nanocomposite (MWCNTs/IL/CCE). Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) and chronoamperometry methods were used for electrochemical studies and measurements, respectively. The obtained results show that the MWCNTs/IL/CCE exhibited high electrocatalytic activity towards the oxidation of PHE. Under the optimum conditions, the anodic peak current in DPV is linear to the PHE concentration over the ranges of 3×10-7 M-100×10-6 M with a correlation coefficient of 0.998 and detection limit of 1.7×10-7 M. DPV was also used for simultaneous determination of PHE and AC in the same conditions. The stability, reproducibility and repeatability of the modified electrode were investigated and obtained relative standard deviations show that the MWCNTs/IL/CCE has excellent stability, reproducibility and repeatability. Finally, the nanocomposite modified electrode was effectively applied for determination of PHE and AC in some real samples without any interference.

Keywords

Multi-walled carbon nanotubes

Ionic liquid

Nanocomposite

Carbon-ceramic electrode

Phenylephrine

‎Acetaminophen.‎